منابع مشابه
Unusual ophthalmic manifestation in chronic myeloid leukemia: A case report
Background: Chronic myeloid leukemia (CML) is a myeloproliferative hematopoietic malignancy with a heterogeneous proliferation of hematopoietic cells in the bone marrow. The ocular manifestations are rare symptoms of CML. In this case report, a CML patient with retinal hemorrhage is reported as an uncommon symptom. Case presentation: A 35-year-old man was referred due to decreased right eye vi...
متن کاملUpdate of recent studies in chronic myeloid leukemia
The use of tyrosine kinase inhibitors (TKIs) has dramatically improved outcomes for patients with chronic myeloid leukemia (CML). The IRIS study is the definitive phase III trial of imatinib mesylate as frontline therapy for CML. Seven year follow-up data has recently been reported [1]. The overall survival (including deaths from all causes) is 86% and the event free survival is 81% at seven ye...
متن کاملThe role of microRNA in acute/chronic, myeloid/lymphocytic leukemia
MicroRNAs are small, non-coding sequences that regulate gene expression by inducing degradation or translational inhibition of target mRNAs. These molecules control many intracellular physiological and pathological processes.Abnormal expression of these moleculs has been described in different cancers including hematopoietic cancers. According to the type of cancer and the stage, miRNA’s expres...
متن کاملAn update on chronic myeloid leukaemia.
The therapy of CML is clearly 'work in progress' Although long-term follow-up data for patients treated with STI571 are not yet available, preliminary results are encouraging. STI571 is likely to be licensed in late 2001/early 2002 and will certainly find a place in the treatment of CML. Current therapeutic considerations are summarised in Fig 2. At all stages of treatment it is vital that the ...
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ژورنال
عنوان ژورنال: Revista da Associação Médica Brasileira (English Edition)
سال: 2013
ISSN: 2255-4823
DOI: 10.1016/s2255-4823(13)70482-x